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Antigenic Specificity | Bovine Interferon tau-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the concept |
Immunogen | Immunogen: Recombinant Bovine Interferon tau-1 protein(24-195AA) |
Other Names | [Antiluteolysin; Trophoblast antiluteolytic protein; Trophoblast protein 1; Trophoblastin; IFNT1], [IFNT2; IFNT1; IFNT; TP-1; IFNT1; IFN-tau-c2; IFN-tau-1; TP-1] |
Gene, Accession # | Gene ID: 317698, NCBI: NP_001015511.3, UniProt: P15696 |
Catalog # | MBS968992 |
Price | $160, $235 |
Order / More Info | Bovine Interferon tau-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |