Edit |   |
---|---|
Antigenic Specificity | TrkB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, chicken |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 200 ug/ml |
Applications | Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Due to the various splice variants, the trk proteins exist as variably glycosylated entities with the major forms having molecular weights of 140 145 kDa, 110 kDa and the unglycosylated form of 80 kDa. trkB contains 33. 3% carbohydrate by weight representing modification on 10 of 12 N glycosylation sites. The primary ligand for trkB is BDNF which induces the phosphorylation of the protein and subsequent binding of PLC gamma via SH2 domains. TrkB may function to modulate neuronal responses to the neurotrophins acting through trkB such as BDNF. |
Immunogen | Immunogen: TrkB antibody was raised in Rabbit using synthetic peptide surrounding amino acid 810 of human TrkB as the immunogen. |
Other Names | [Rabbit TrkB; TrkB; TrkB; TrkB] |
Gene, Accession # | [TrkB], Gene ID: 4915, NCBI: AAB33109.1 |
Catalog # | MBS5309143 |
Price | $680 |
Order / More Info | TrkB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |