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Antigenic Specificity | JMJD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: bovine, horse, sheep, rabbit, dog |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: JMJD3 Antibody detects endogenous levels of JMJD3. Description: Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Demethylates trimethylated and dimethylated H3 'Lys-27' (PubMed:17825402, PubMed:17851529, PubMed:17713478, PubMed:18003914). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402). Plays a demethylase-independent role in chromatin remode |
Immunogen | Immunogen: A synthesized peptide derived from human JMJD3. Tissue Specificity: By 12-O-tetradecanoylphorbol-13-acetate (TPA) in myeloid leukemia cells. |
Other Names | [Histone demethylase JMJD3; JmjC domain containing protein 3; JmjC domain-containing protein 3; Jumonji D3; Jumonji domain containing 3; Jumonji domain containing 3 histone lysine demethylase; Jumonji domain containing protein 3; Jumonji domain-containing protein 3; Kdm6b; KDM6B_HUMAN; KIAA0346; Lysine demethylase 6B; Lysine K specific demethylase 6B; Lysine specific demethylase 6B; Lysine-specific demethylase 6B] |
Gene, Accession # | [JMJD3], Gene ID: 23135, NCBI: EAW90126, UniProt: O15054 |
Catalog # | MBS9611851 |
Price | $240, $280 |
Order / More Info | JMJD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |