Edit |   |
---|---|
Antigenic Specificity | Phospho-PPP2CA (Y307) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-PPP2CA (Y307) |
Other Names | [Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; RP-C; PPP2CA] |
Gene, Accession # | [PPP2CA], Gene ID: 5515, NCBI: NP_002706.1, UniProt: P67775 |
Catalog # | MBS7114880 |
Price | $185, $265 |
Order / More Info | Phospho-PPP2CA (Y307) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |