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Antigenic Specificity | Phospho-eIF4G (Ser1185) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-eIF4G (Ser1185) Antibody detects endogenous levels of eIF4G only when phosphorylated at Ser1185. Description: Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.Post Translational Modifications: Phosphorylated at multiple sites in vivo. Phosphorylation at Ser-1185 by PRKCA induces binding to MKNK1. Following infection by certain enteroviruses, rhinoviruses and aphthoviruses, EIF4G1 is cleaved by the viral protease 2A, or the leader protease in the case of aphthoviruses. This shuts down the capped cellular mRNA transcription.Subunit Structure: eIF4F is a multi-subun |
Immunogen | Immunogen: A synthesized peptide derived from human eIF4G around the phosphorylation site of Ser1185. |
Other Names | [DKFZp686A1451; eIF 4 gamma 1; eIF 4G 1; eIF 4G1; eIF-4-gamma 1; eIF-4G 1; eIF-4G1; EIF4 gamma; EIF4F; EIF4G; EIF4G1; EIF4GI; Eukaryotic translation initiation factor 4 gamma 1; IF4G1_HUMAN; p220] |
Gene, Accession # | [eIF4G], Gene ID: 1981, NCBI: NP_886553.3, UniProt: Q04637 |
Catalog # | MBS9610712 |
Price | $225, $280, $340 |
Order / More Info | Phospho-eIF4G (Ser1185) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |