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Antigenic Specificity | TL1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | DEAE purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TL1A will not cross-react with TL1. Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl-1, Apo-3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3/TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NF-kB activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL-1. TL1A is a longer variant of TL1 (also called VEGI). |
Immunogen | Immunogen Type: Recombinant protein Immunogen Description: Raised against recombinant human TL1A. |
Other Names | [TNF superfamily ligand TL1A; Tumor necrosis factor ligand superfamily member 15; tumor necrosis factor ligand superfamily member 15; tumor necrosis factor (ligand) superfamily, member 15; TNF ligand-related molecule 1; Vascular endothelial cell growth inhibitor] |
Gene, Accession # | [TL1A], Gene ID: 9966, NCBI: AAM77366 |
Catalog # | MBS9407243 |
Price | $320 |
Order / More Info | TL1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |