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Antigenic Specificity | GCGR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system. |
Immunogen | Immunogen: Recombinant Human Glucagon receptor protein (26-136AA) |
Other Names | [Glucagon receptorGL-R; GCGR] |
Gene, Accession # | [GCGR], Gene ID: 2642, NCBI: NP_000151.1, UniProt: P47871 |
Catalog # | MBS7048238 |
Price | $160, $235 |
Order / More Info | GCGR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |