TXNIP Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TXNIP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TXNIP antibody is human, mouse and rat reactive. Thioredoxin-interacting protein (TXNIP) belongs to the arrestin family and plays a critical role in the antioxidant defense mechanisms of hematopoietic cells by activating the p53 pathway during oxidative stress (1,2). It functions as a transcriptional repressor and acts as an oxidative stress mediator by inhibiting thioredoxin activity (2). TXNIP expression is reduced in many types of tumors, and TXNIP overexpression inhibits tumor growth by blocking cell-cycle progression (3). It has recently reported that TXNIP deficiency correlates with a high incidence of hepatocellular carcinoma (HCC) (4). TXNIP and p53 interactions could potentially be a therapeutic target for oxidative st |
| Immunogen | Immunogen: TXNIP antibody was raised against a 16 amino acid peptide near the center of human TXNIP. Buffer: TXNIP antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [Thioredoxin-interacting protein; BMP and activin membrane-bound inhibitor homolog; non-metastatic gene A protein; NMA; thioredoxin interacting protein], [TXNIP; TXNIP; THIF; VDUP1; HHCPA78; EST01027; VDUP1] |
| Gene, Accession # | [TXNIP], Gene ID: 10628, NCBI: NP_006463 |
| Catalog # | MBS153657 |
| Price | $375 |
| Order / More Info | TXNIP Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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