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Antigenic Specificity | CTNND1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Catenin delta-1 (p120 catenin) has an amino-terminal coiled-coil domain followed by a regulatory domain containing multiple phosphorylation sites and a central Armadillo repeat domain of ten linked 42-amino acid repeats. The carboxy-terminal tail has no known function (1). Catenin delta-1 fulfills critical roles in the regulation of cell-cell adhesion as it regulates E-cadherin turnover at the cell surface to determine the level of E-cadherin available for cell-cell adhesion (2). Catenin delta-1 has both positive and negative effects on cadherin-mediated adhesion (3). Actin dynamics are also regulated by catenin delta-1, which modulates RhoA, Rac, and cdc42 proteins (1). Analogous to beta-catenin, catenin delta-1 translocates to the nucleus |
Immunogen | Immunogen: Recombinant protein of human CTNND1 Calculated MW: 65-72kDa/90-108kDa Observed MW: 105kDa |
Other Names | [CAS; CTNND; KIAA0384; P120CAS; P120CTN; p120] |
Gene, Accession # | [CTNND1], Gene ID: 1500, NCBI: NP_001193814.1 |
Catalog # | MBS2524951 |
Price | $150, $225, $360 |
Order / More Info | CTNND1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |