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Antigenic Specificity | Phospho-PKD/PKCmu-S744/748 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response. Phosphorylates the epidermal growth factor receptor (EGFR) on dual threonine residues, which leads to the suppression of epidermal growth factor (EGF)-induced MAPK8/JNK1 activation and su |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding S744/748 of human PKD/PKCmu |
Other Names | [PKD; PKCM; CHDED; PRKCM; PKC-MU; PRKD1] |
Gene, Accession # | [PKD/PKCmu], Gene ID: 5587, NCBI: NP_002733.2, UniProt: Q15139 |
Catalog # | MBS8550644 |
Price | $280 |
Order / More Info | Phospho-PKD/PKCmu-S744/748 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |