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Antigenic Specificity | MLL3 |
Clone | [1686CT202.60.69] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,k |
Format | purified |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MLL3 antibody is generated from a mouse immunized with a recombinant protein of human MLL3. Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder. |
Immunogen | n/a |
Other Names | [Histone-lysine N-methyltransferase 2C; Lysine N-methyltransferase 2C; 2.1.1.43; Homologous to ALR protein; Myeloid/lymphoid or mixed-lineage leukemia protein 3; KMT2C; HALR; KIAA1506; MLL3] |
Gene, Accession # | [KMT2C], Gene ID: 58508, NCBI: NP_733751.2, UniProt: Q8NEZ4 |
Catalog # | MBS9217045 |
Price | $165, $370 |
Order / More Info | MLL3 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ruault M.,et al.Gene 284:73-81 (2002). Tan Y.C.,et al.Cancer Detect. Prev. 25:454-469 (2001). Hillier L.W.,et al.Nature 424:157-164 (2003). Nagase T.,et al.DNA Res. 7:143-150 (2000). Nakajima D.,et al.DNA Res. 9:99-106 (2002). |