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Antigenic Specificity | Human CD63 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB); ELISA (EIA); Flow Cytometry (FC/FACS); Immunoprecipitation (IP); Immunohistochemistry (IHC) Formalin/Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal unconjugated antibody to detect CD63 in human samples. Anti-CD63 recognizes an extracellular fragment of CD63; a 56-kilodalton (kDa); type III lysosomal glycoprotein; belonging to the tetraspanin family. CD63 is expressed by granulocytes; platelets; T-cells; monocytes/macrophages; endothelial cells. CD63 protein is also expressed in exosome membrane. Cell sur-face exposition of CD63 is usually activation dependent. CD63 interacts with integrins and affects phagocytosis and cell migration; it is also involved in H/K ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell co-stimulator molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. |
Immunogen | Immunogen: T-cell line HRB-ALL |
Other Names | n/a |
Gene, Accession # | [CD63] |
Catalog # | MBS846149 |
Price | $420 |
Order / More Info | Human CD63 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |