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Antigenic Specificity | BACE2 A/C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 0.72-0.76 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Beta Secretase beta-site APP cleaving Enzyme 2A/C Antibody. Responsible for the proteolytic processing of the amyloid precursor protein. Cleaves APP between 690 and 691 leading to the generation and extracellular release of beta-cleaved soluble APP and C-terminal fragment which is later released by gamma-secretase. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 490-518 on human BACE2 protein. Expression: Neurons within the hippocampus, frontal cortex and temporal cortex. Lower expression in most peripheral tissues and at higher levels in colon, kidney, pancreas, placenta, prostate, stomach and trachea. Also found in spinal cord, medulla oblongata, substania nigra and locus coruleus. Expressed in ductal epithelium of prostate. |
Other Names | [ALP 56; ASP1; ASP21; Aspartic Like Protease 56kDa; Downs Syndrome Region Aspartic Protease; DRAP; Memapsin-1; Membrane associated aspartic protease 1; Theta-secretase], [BACE2; BACE2; ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1; AEPLC; ALP56; ASP21; ASP1; Asp 1; Beta-site APP cleaving enzyme 2; DRAP] |
Gene, Accession # | [BACE2 A/C], Gene ID: 25825, NCBI: AAQ89286, UniProt: Q9Y5Z0 |
Catalog # | MBS540534 |
Price | $390 |
Order / More Info | BACE2 A/C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |