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Antigenic Specificity | HSPA8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation (PubMed:21150129, PubMed:21148293, PubMed:24732912, PubMed:27916661, PubMed:23018488). This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones (PubMed:21150129, PubMed:21148293, PubMed:24732912, PubMed:279166 |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human HSPA8 (NP 006588.1). |
Other Names | [LAP1; HSC54; HSC70; HSC71; HSP71; HSP73; LAP-1; NIP71; HEL-33; HSPA10; HEL-S-72p] |
Gene, Accession # | [HSPA8], Gene ID: 3312, NCBI: NP_006588.1, UniProt: P11142 |
Catalog # | MBS8544932 |
Price | $280 |
Order / More Info | HSPA8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |