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Antigenic Specificity | EIF2AK2 (pThr446) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti EIF2AK2 (pThr446) antibody recognizes interferon-induced, double-stranded RNA-activated protein kinase when phosphorylated on threonine 446. EIF2AK2 is a serine/threonine protein kinase which is activated by double-stranded RNA (dsRNA) and phosphorylates the alpha subunit of eukaryotic initiation factor 2 (eIF2alpha) (Hershey 1991). EIF2AK2 is induced by kisspeptin and its activation inhibits cancer growth (Kim and Cho 2017). Autophosphorylation of EIF2AK2 at threonine 446 is critical for kinase activity (Zhang et al. 2001). |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding serine threonine 446 of human EIF2AK2 |
Other Names | [EIF2AK2 (pThr446)], [EIF2AK2; EIF2AK2; PKR; PRKR; EIF2AK1; PPP1R83; PKR; PRKR; eIF-2A protein kinase 2; PKR] |
Gene, Accession # | [EIF2AK2], Gene ID: 5610, NCBI: NP_001129123.1, UniProt: P19525 |
Catalog # | MBS225611 |
Price | $375 |
Order / More Info | EIF2AK2 (pThr446) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |