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Antigenic Specificity | Human APOLIPOPROTEIN E |
Clone | [WUE-4] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human Apolipoprotein E antibody, clone WUE-4 recognizes an epitope within amino acids 140-160 of human apolipoprotein E (Apo-E), a major component of very low-density lipoproteins (VLDLs). Apo-E is the principle apolipoprotein in the central nervous system, and is secreted by most organs into the plasma, playing a vital role in the binding, internalization and catabolism of triglyceride-rich lipoprotein constituents. Apo-E acts as a ligand for both the specific apo-E receptor (chylomicron remnant) of hepatic tissues, and the apoB,E (LDL) receptor. Three isoforms of Apo-E have been identified, ApoE2, E3 and E4, and have been linked with various disorders. ApoE2 has been shown to bind LPL receptors with low affinity, resulting in i |
Immunogen | Immunogen: Purified ApoHDL fraction Fusion Partners: Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/O-Ag14 mouse myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [apolipoprotein E isoform b; Apolipoprotein E; apolipoprotein E; apolipoprotein E3; apolipoprotein E], [APOE; APOE; AD2; LPG; APO-E; LDLCQ5; Apo-E] |
Gene, Accession # | Gene ID: 348, NCBI: NP_000032.1, UniProt: P02649 |
Catalog # | MBS224394 |
Price | $300 |
Order / More Info | Human APOLIPOPROTEIN E Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |