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Antigenic Specificity | MMP-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MMP-2 protein. Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-cat |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human MMP-2. |
Other Names | [CLG4A; COLLAGENASE TYPE IV; 72-KD; COLLAGENASE TYPE IV-A; GELATINASE] |
Gene, Accession # | [MMP-2], Gene ID: 4313, NCBI: NP_001121363.1, UniProt: P08253 |
Catalog # | MBS9414998 |
Price | $200, $255 |
Order / More Info | MMP-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |