Edit |   |
---|---|
Antigenic Specificity | Bcl-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, human |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes both Bcl-2 alpha and beta isoforms. Human Bcl-2 alpha is a 239 amino acid (aa) protein and human Bcl-2 beta is a 205 aa protein. The Bcl-2 family of apoptosis-related genes plays central roles in regulating apoptotic pathways. Regulation of cell death through apoptosis is critical for the maintenance of homeostasis, defense against infectious agents, and normal development. Bcl-2 family proteins regulate apoptosis primarily through the regulation of mitochondrial outer membrane permeability. In mammals, Bcl-2 family proteins can be divided into 3 main subfamilies on the basis of their function and the content of their Bcl-2 homology (BH) domains, for example: 1) Prosurvival: Bcl-2, Bcl-XL, Bcl-W, A1, and Mcl-1 2) Pr |
Immunogen | Immunogen Information: A synthetic peptide of Bcl-2 protein (amino acids 41-54 GAAPAPGIFSSQPG) was used as the immunogen for this antibody |
Other Names | [BCL2; Apoptosis regulator Bcl-2; to Bcl-2; Bcl-2; Bcl-2], [BCL2; BCL2; Bcl-2; PPP1R50] |
Gene, Accession # | [BCL2], Gene ID: 596, NCBI: P10415.2, UniProt: P10415 |
Catalog # | MBS668538 |
Price | $270 |
Order / More Info | Bcl-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |