Edit |   |
---|---|
Antigenic Specificity | Granzyme B |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Rabbit IgG Monoclonal antibody for P10144 detection. Tested positive for IHC IF/IF IP in Human |
Immunogen | Immunogen: A synthesized peptide derived from human Granzyme B This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. |
Other Names | [granzyme B isoform 1 preproprotein; Granzyme B; granzyme B; granzyme B; C11; CTLA-1; Cathepsin G-like 1; CTSGL1; Cytotoxic T-lymphocyte proteinase 2; Lymphocyte protease; Fragmentin-2; Granzyme-2; Human lymphocyte protein; HLP; SECT; T-cell serine protease 1-3E] |
Gene, Accession # | [GZMB], Gene ID: 3002, NCBI: NP_004122.2, UniProt: P10144 |
Catalog # | MBS1751947 |
Price | $160, $340, $340 |
Order / More Info | Granzyme B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |