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Antigenic Specificity | AGTR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G proteinassociated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLC(c) is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an |
Immunogen | Immunogen: A synthetic peptide of human AGTR1 |
Other Names | [AGTR1; AT1; AG2S; AT1B; AT1R; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1A; AGTR1B; AT2R1A; AT2R1B], [AGTR1; AGTR1; AT1; AG2S; AT1B; AT1R; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1A; AGTR1B; AT2R1A; AT2R1B; AGTR1A; AGTR1B; AT2R1; AT2R1B; AT1] |
Gene, Accession # | Gene ID: 185, NCBI: NP_000676.1, UniProt: P30556 |
Catalog # | MBS127051 |
Price | $275, $430 |
Order / More Info | AGTR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |