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Antigenic Specificity | Phospho-MYC-S62 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its import |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding S62 of human MYC Calculated Molecular Weight: 60kDa |
Other Names | [Phospho-MYC-S62: MRTL; MYCC; c-Myc; bHLHe39], [MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39] |
Gene, Accession # | [MYC], Gene ID: 4609, NCBI: P01106.1, UniProt: P01106 |
Catalog # | MBS128476 |
Price | $235, $350, $525 |
Order / More Info | Phospho-MYC-S62 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |