Mouse Txnip (Center), 116-145 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Txnip (Center), 116-145 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse (predicted reactivity: rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.47 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Txnip antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-145 amino acids from the Central region of mouse Txnip. May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. |
| Immunogen | n/a |
| Other Names | [Thioredoxin-interacting protein; Vitamin D3 up-regulated protein 1; Txnip; Vdup1] |
| Gene, Accession # | [Txnip], Gene ID: 56338, NCBI: NP_001009935.1, UniProt: Q8BG60 |
| Catalog # | MBS9206760 |
| Price | $165, $370 |
| Order / More Info | Mouse Txnip (Center), 116-145 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Kwon, H.J., et al. Toxicol. Appl. Pharmacol. 248(3):277-284(2010) Kwon, H.J., et al. J. Immunol. 185(7):3980-3989(2010) Ren, Y., et al. FEBS Lett. 584(15):3480-3485(2010) Chutkow, W.A., et al. Diabetes 59(6):1424-1434(2010) Shao, Y., et al. Immunol. Lett. 129(2):78-84(2010) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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