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Antigenic Specificity | Cyclin D1 (Phospho-Ser90) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of Cyclin D1 only when phosphorylated at serine 90. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.Sewing A, M??ller R (1994) Oncogene 9, 2733-6 |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 90(F-L-S(p)-L-E) derived from Human Cyclin D1. |
Other Names | [BCL1; CCND1; CYL-1; PRAD1; PRAD1 oncogene] |
Gene, Accession # | Gene ID: 595, NCBI: NP_444284.1, UniProt: P24385 |
Catalog # | MBS9401518 |
Price | $200, $255 |
Order / More Info | Cyclin D1 (Phospho-Ser90) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |