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Antigenic Specificity | TLR8/CD288 |
Clone | [ABM15F6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Toll like receptor 8, also known as CD288, is a member of TLR family. It plays an important role in sensing phagocytosed pathogen. TLR8 recognizes ssRNA and recruits MyD88 and leads to the activation of transcription factor NF-kappa B. TLR8 TLR8 has two splice variants, viz., TLR8v1 and TLR8v2 and one missense variant, termed G or A1G allele of TLR8. TLR8v1 has additional 19 amino acids in the N-terminus. It is predominantly expressed in lung and peripheral blood leukocytes. |
Immunogen | Antigen: TLR8/CD288. Immunogen Information: A partial length recombinant TLR8 protein (amino acids 750-900) was used as the immunogen for this antibody. Conjugation: Unconjugated |
Other Names | [TLR8; UNQ249/PRO286; CD288], [TLR8; TLR8; CD288] |
Gene, Accession # | [TLR8], Gene ID: 51311, NCBI: NP_057694.2, UniProt: Q9NR97 |
Catalog # | MBS668955 |
Price | $290 |
Order / More Info | TLR8/CD288 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |