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Antigenic Specificity | CD45RA |
Clone | [HI100] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | fluorescein (FITC) conjugate |
Size | 25 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal FITC conjugated antibody to detect CD45RA in human samples. Background: CD45, a transmembrane multifunctional glycoprotein, is a member of Type I receptor-linked PTPase family and is expressed as multiple isoforms due to alternative splicing. Expression of these isoforms is highly regulated and shift in this expression determines T-cell activation. CD45RB consists of exon B and is predominantly expressed in naive T-cells secreting IL-2. Its expression is low in primed/memory T cells, cells that express Th2 cytokines such as IL-4 and IL-10 and population of T-cells with regulatory function. Immunotherapy with CD45RB antibody is being widely studied in transplantation and vaccination. CD45 antibodies are commonly used to iden |
Immunogen | Immunogen: Human CD45RA. Positive Control: FACS: Human peripheral blood lymphocytes |
Other Names | [CD45RA], [PTPRC; PTPRC; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; CD45; L-CA] |
Gene, Accession # | [CD45RA], Gene ID: 5788, NCBI: NP_002829.3, UniProt: P08575 |
Catalog # | MBS840008 |
Price | $160, $290 |
Order / More Info | CD45RA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |