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Antigenic Specificity | PDXK (C-term), 242-272 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PDXK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-272 amino acids from the C-terminal region of human PDXK. Pyridoxal kinase (PDXK) converts vitamin B6 to pyridoxal-5-phosphate (PLP), an essential cofactor in the intermediate metabolism of amino acids and neurotransmitters. The PDXK gene encodes a 312-amino acid polypeptide, and expression of the cDNA reveals pyridoxal kinase activity. Northern blot analysis revealed that a major 1.5-kb PDXK transcript is expressed in all tissues tested. The expression of PDXK shows circadian oscillations. The expression of Pdxk in mouse liver and brain is regulated by the 3 PAR bZIP transcription factors, Dbp, Hlf, and Tef, which also show circadian |
Immunogen | n/a |
Other Names | [Pyridoxal kinase; Pyridoxine kinase; PDXK; C21orf124; C21orf97; PKH; PNK] |
Gene, Accession # | [PDXK], Gene ID: 8566, NCBI: NP_003672.1, UniProt: O00764 |
Catalog # | MBS9208810 |
Price | $165, $370 |
Order / More Info | PDXK (C-term), 242-272 Antibody from MYBIOSOURCE INC. |
Product Specific References | Shin, J.H., et al., Neurochem. Int. 45(1):73-79 (2004). Lee, H.S., et al., Mol. Cells 10(4):452-459 (2000). Laine-Cessac, P., et al., Biochem. Pharmacol. 54(8):863-870 (1997). Hanna, M.C., et al., J. Biol. Chem. 272(16):10756-10760 (1997). Zhang, Z., et al., J. Nutr. 10(1):53-59 (1993). |