DNA Polymerase alpha Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-DNA Polymerase alpha antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | DNA Polymerase alpha |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: DNA Polymerase alpha antibody detects endogenous levels of total DNA Polymerase alpha. Function: Plays an essential role in the initiation of DNA replication. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1/p180, a regulatory subunit POLA2/p70 and two primase subunits PRIM1/p49 and PRIM2/p58) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase |
| Immunogen | Immunogen: A synthesized peptide derived from human DNA Polymerase alpha Subcellular Location: Nucleus. Predicted Cross Reactivity: Pig, Bovine, Horse Similarity: Pig (91%), Bovine (80%), Horse (91%) |
| Other Names | [DKFZp686K1672; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DPOLA_HUMAN; OTTHUMP00000023089; OTTHUMP00000023090; P180; p180 subunit; POLA; POLA1; Polymerase (DNA directed), alpha 1, catalytic subunit; Polymerase (DNA-directed), alpha (70kD)] |
| Gene, Accession # | [POLA1], Gene ID: 5422, NCBI: NP_058633.2, UniProt: P09884 |
| Catalog # | MBS9601408 |
| Price | $240, $280 |
| Order / More Info | DNA Polymerase alpha Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies