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Antigenic Specificity | BAF250B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: BAF250B antibody detects endogenous levels of total BAF250B. Function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to the |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nuclear Tissue Specificity: Widely expressed with high levels in heart, skeletal muscle and kidney. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (91%), Horse (100%), Sheep (91%), Rabbit (100%), Dog (100%), Chicken (91%) |
Other Names | [6A3 5; ARID 1B; ARID domain containing protein 1B; AT rich interactive domain 1B (SWI1 like); AT rich interactive domain 1B; AT rich interactive domain containing protein 1B; BAF 250b; BAF-associated factor, 250-KD, B; BAF250b; BRG1 associated factor 250b; BRG1 binding protein; BRG1 binding protein ELD/OSA1; BRG1 binding protein hELD/OSA1; BRIGHT; DAN 15; DAN15; Eld (eyelid)/Osa protein; ELD/OSA1; hELD/OSA1; hOsa 2; hOsa2; KIAA1235; MRD12; OSA 2; Osa homolog 2; OSA2; OTTHUMP00000040115; p250R; RP11 419L10.1] |
Gene, Accession # | [BAF250B], Gene ID: 57492, NCBI: NP_001333742.1, UniProt: Q8NFD5 |
Catalog # | MBS9604819 |
Price | $240, $280 |
Order / More Info | BAF250B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |