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Antigenic Specificity | CDK5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human , mouse , rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemuistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CDK5 Antibody detects endogenous levels of total Cdk5. Swiss-Prot Acc.Q00535.Activated by cyclins but by p35 (CDK5R1) and p39. An important regulator of neuronal positioning during brain development. May also play a role in synaptogenesis and neurotransmission. Substrates include TAU, MAP2, NF-H and -M, Nudel, PDE6, beta-catenin, amphyphysin, dynamin I, synapsin 1, Munc-18, and NMDA receptor 2A. Plays a role in myogenesis, haematopoietic cell differentiation, spermatogenesis, insulin secretion, and lens differentiation. |
Immunogen | Immunogen: A synthesized peptide derived from human Cdk5 Sensitivity: Isoform 1 is ubiquitously expressed. Accumulates in cortical neurons (at protein level). Isoform 2 has only been detected in testis, skeletal muscle, colon, bone marrow and ovary. |
Other Names | [CDK5; CRK6; Cell division protein kinase 5; EC 2.7.11.22; PSSALRE; TAU protein kinase II catalytic subunit; TPKII catalytic subunit; Tau protein kinase II catalytic subunit; kinase Cdk5;] |
Gene, Accession # | [CDK5], Gene ID: 1020, NCBI: NP_001157882.1, UniProt: Q00535 |
Catalog # | MBS4750174 |
Price | $335 |
Order / More Info | CDK5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |