WNK2 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | WNK2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SLC12A2, SCNN1A, SCNN1B, SCNN1D and SGK1 and inhibits SLC12A5. Negatively regulates the EGF-induced activation of the ERK/MAPK-pathway and the downstream cell cycle progression. Affects MAPK3/MAPK1 activity by modulating the activity of MAP2K1 and this modulation depends on phosphorylation of MAP2K1 by PAK1. WNK2 acts by interfering with the activity of PAK1 by controlling the balance of the activity of upstream regulators of PAK1 activity, RHOA and RAC1 |
| Immunogen | Immunogen: Recombinant Human Serine/threonine-protein kinase WNK2 protein (1177-1464AA) |
| Other Names | [Serine/threonine-protein kinase WNK2; Antigen NY-CO-43; Protein kinase lysine-deficient 2; Protein kinase with no lysine 2; Serologically defined colon cancer antigen 43; WNK2; KIAA1760; PRKWNK2; SDCCAG43; P/OKcl.13] |
| Gene, Accession # | [WNK2], Gene ID: 65268, NCBI: NP_001269323.1, UniProt: Q9Y3S1 |
| Catalog # | MBS7104345 |
| Price | $160, $235 |
| Order / More Info | WNK2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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