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Antigenic Specificity | Twinfilin-1 |
Clone | [5F10-H11-D5] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1. UniPort Summary Function: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). |
Immunogen | Immunogen: Purified recombinant fragment of human TWF1 (AA: 335-384) expressed in E Coli. Sequence Similarities: Contains 2 ADF-H domains. |
Other Names | [A6; PTK9; MGC23788; MGC41876], [A6; PTK9; MGC23788; MGC41876] |
Gene, Accession # | [TWF1], Gene ID: 5756, NCBI: NP_001229326.1, UniProt: Q12792 |
Catalog # | MBS476344 |
Price | $335 |
Order / More Info | Twinfilin-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |