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Antigenic Specificity | SPAK (Phospho Ser311) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-SPAK (S311) Polyclonal Antibody detects endogenous levels of SPAK protein only when phosphorylated at S311. STK39 encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. |
Immunogen | Immunogen: Synthesized peptide derived from human SPAK around the phosphorylation site of S311 |
Other Names | [Rabbit SPAK (phospho Ser311); STK39; SPAK; STE20/SPS1-related proline-alanine-rich protein kinase; Ste-20-related kinase; DCHT; Serine/threonine-protein kinase 39] |
Gene, Accession # | [SPAK], Gene ID: 27347, NCBI: NP_037365.2, UniProt: Q9UEW8 |
Catalog # | MBS9705196 |
Price | $130, $220, $325 |
Order / More Info | SPAK (Phospho Ser311) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |