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Antigenic Specificity | SPTA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. This complex is anchored to the cytoplasmic face of the plasma membrane via another protein, ankyrin, which binds to beta-spectrin and mediates the binding of the whole complex to a transmembrane protein band 3. The interaction of erythrocyte spectrin with other proteins through specific binding domains lead to the formation of an extensive subplasmalemmal meshwork which is thought to be responsible for the maintenance of the biconcave shape of human erythrocytes, for the regulation of plasma membrane components and for the |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 940-1160 of human SPTA1 (NP 003117.2). |
Other Names | [EL2; HPP; HS3; SPH3; SPTA] |
Gene, Accession # | [SPTA1], Gene ID: 6708, NCBI: P02549.5, UniProt: P02549 |
Catalog # | MBS8548197 |
Price | $280 |
Order / More Info | SPTA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |