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Antigenic Specificity | DBLOH |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of DBLOH protein. DIABLO encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in DIABLO is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human DBLOH protein |
Other Names | [Rabbit DBLOH; Diablo homolog; mitochondrial; Direct IAP-binding protein with low pI; Second mitochondria-derived activator of caspase; Smac] |
Gene, Accession # | [DBLOH], Gene ID: 56616, NCBI: AAF87716.1, UniProt: Q9NR28 |
Catalog # | MBS9708912 |
Price | $130, $220, $325 |
Order / More Info | DBLOH Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |