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Antigenic Specificity | Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) |
Clone | [PODXL/2185] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology. |
Immunogen | Immunogen: Recombinant fragment of human Podocalyxin (around aa 310-447) Cellular Localization: Cell Surface and Cytoplasmic |
Other Names | [PODXL, PDXL, GCTM-2; Gp200; PCLP1; Pcx; Podocalyxin-like protein 1] |
Gene, Accession # | [PODXL], Gene ID: 5420, NCBI: NP_001018121.1, UniProt: O00592 |
Catalog # | MBS4380473 |
Price | $190, $340, $340 |
Order / More Info | Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Kershaw DB et. al. J Biol Chem 272:15708-15714 (1997). Sassetti C et. al. J Exp Med 187:1965-1975. 3. Nielsen JS et. al. J Am Soc Nephrol 20:1669-1676 (2009). |