Edit |   |
---|---|
Antigenic Specificity | TXNRD1 (C-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse; predicted reactivity: mouse, porcine, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TXNRD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 516-550 amino acids from human TXNRD1. Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid. |
Immunogen | n/a |
Other Names | [Thioredoxin reductase 1; cytoplasmic; TR; 1.8.1.9; Gene associated with retinoic and interferon-induced mortality 12 protein; GRIM-12; Gene associated with retinoic and IFN-induced mortality 12 protein; KM-102-derived reductase-like factor; Thioredoxin reductase TR1; TXNRD1; GRIM12; KDRF] |
Gene, Accession # | [TXNRD1], Gene ID: 7296, NCBI: NP_001087240.1, UniProt: Q16881 |
Catalog # | MBS9217303 |
Price | $165, $370 |
Order / More Info | TXNRD1 (C-Term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Gasdaska P.Y.,et al.FEBS Lett. 373:5-9 (1995). Koishi R.,et al.J. Biol. Chem. 272:2570-2577 (1997). Hofman E.R.,et al.Mol. Cell. Biol. 18:6493-6504 (1998). Rundloef A.-K.,et al.Free Radic. Biol. Med. 36:641-656 (2004). Schuetze N.,et al.Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases. |