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Antigenic Specificity | ADAM10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles, suggesting a vesicle-based protease activity. Controls also the proteolytic processing of Notch and mediates lateral inhibition during neurogenes |
Immunogen | Immunogen: Recombinant human Disintegrin and metalloproteinase domain-containing protein 10 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-16523 / sc-31853 / sc-31855 / sc-16524 / sc-25578 |
Other Names | [Disintegrin and metalloproteinase domain-containing protein 10 (EC:3.4.24.81); ADAM 10; ADAM10; KUZ; MADM; CDw156; Kuzbanian protein homolog; Mammalian disintegrin-metalloprotease; CD_antigen: CD156c], [ADAM10; ADAM10; RAK; kuz; AD10; AD18; MADM; CD156c; HsT18717; KUZ; MADM; ADAM 10] |
Gene, Accession # | [ADAM10], Gene ID: 102, NCBI: NP_001101.1, UniProt: O14672 |
Catalog # | MBS1493874 |
Price | $160, $235 |
Order / More Info | ADAM10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |