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Antigenic Specificity | TELO2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TELO2 antibody detects endogenous levels of TELO2. Function: Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation. |
Immunogen | Immunogen: A synthesized peptide derived from human TELO2. Subcellular Location: Cytoplasm. Membrane. Nucleus. Chromosome > Telomere. Predicted Cross Reactivity: Pig, Bovine, Horse, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (91%) |
Other Names | [CLK2; hCLK2; KIAA0683; Protein clk-2 homolog; TEL2; TEL2 telomere maintenance 2 homolog; TEL2, telomere maintenance 2, homolog; telo2; TELO2_HUMAN; Telomere length regulation protein TEL2 homolog; Telomere maintenance 2] |
Gene, Accession # | [TELO2], Gene ID: 9894, NCBI: NP_057195.2, UniProt: Q9Y4R8 |
Catalog # | MBS9603366 |
Price | $240, $280 |
Order / More Info | TELO2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |