Edit |   |
---|---|
Antigenic Specificity | Phospho-CREB-S133 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CREB is a bZIP transcription factor that activates target genes through cAMP response elements. CREB is able to mediate signals from numerous physiological stimuli, resulting in regulation of a broad array of cellular responses. While CREB is expressed in numerous tissues, it plays a large regulatory role in the nervous system. CREB is believed to play a key role in promoting neuronal survival, precursor proliferation, neurite outgrowth, and neuronal differentiation in certain neuronal populations (1-3). Additionally, CREB signaling is involved in learning and memory in several organisms (4-6). CREB is able to selectively activate numerous downstream genes through interactions with different dimerization partners. CREB is activated by phosp |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Ser133 of human CREB Calculated Molecular Weight: 43kDa |
Other Names | [Phospho-CREB1-S133: CREB1; CREB; MGC9284], [CREB1; CREB1; CREB; CREB-1; cAMP-responsive element-binding protein 1] |
Gene, Accession # | [CREB1], Gene ID: 1385, NCBI: P16220.2, UniProt: P16220 |
Catalog # | MBS125091 |
Price | $235, $350, $525 |
Order / More Info | Phospho-CREB-S133 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |