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Antigenic Specificity | STK24 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total STK24 protein. Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human STK24. |
Other Names | [EC 2.7.11.1; STE20-like kinase MST3; MST-3; Mammalian STE20-like protein kinase 3] |
Gene, Accession # | [STK24], Gene ID: 8428, NCBI: NP_001027467.2, UniProt: Q9Y6E0 |
Catalog # | MBS9406951 |
Price | $200, $255 |
Order / More Info | STK24 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |