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Antigenic Specificity | NXF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NXF1 antibody detects endogenous levels of total NXF1. Description: NXF1 Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with THOC4 and THOC5. Belongs to the NXF family. Heterodimer with NXT1. Interacts (via NTF2 domain) with NXT1. The formation of NXF1/NXT1 heterodimers is required for the NXF1-mediated nuclear mRNA export. Interacts with NXT2, E1B-AP5, RAE1, THOC4 and with several nucleoporins. Is part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, RENT1, RENT2, RENT3A, RENT3B, THOC4 and/or R |
Immunogen | Immunogen: A synthesized peptide derived from human NXF1 Subcellular Location: Nucleus > Nucleoplasm. Nucleus Speckle. Cytoplasm. Localized predominantly in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex. Shuttles between the nucleus and the cytoplasm. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. Tissue Specificity: Expressed ubiquitously. Predicted Cross Reactivity: Pig, Bovine, |
Other Names | [DKFZp667O0311; DmNXF1; MEX67; MEX67, yeast, homolog of; Mex67p; mRNA export factor TAP; Mvb1; Nuclear RNA export factor 1; Nuclear RNA export factor 1 homolog (S. cerevisiae); nxf 1; NXF1; NXF1_HUMAN; Protein small bristles; Sbr; TAP; Tip associating protein; Tip-associated protein; Tip-associating protein] |
Gene, Accession # | [NXF1], Gene ID: 10482, NCBI: NP_001074960.1, UniProt: Q9UBU9 |
Catalog # | MBS9600306 |
Price | $240, $280 |
Order / More Info | NXF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |