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Antigenic Specificity | PD-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin(IHC-P), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PD-1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of danger signals such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases |
Immunogen | Immunogen: PD-1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human PD-1. The Immunogen is located within amino acids 120-170 of PD-1. Buffer: PD-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [PD-1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Programmed cell death protein 1; Protein PD-1; programmed cell death 1], [PDCD1; PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Protein PD-1; hPD-1] |
Gene, Accession # | [PDCD1], Gene ID: 5133, NCBI: Q15116.3, UniProt: Q15116 |
Catalog # | MBS150938 |
Price | $375 |
Order / More Info | PD-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |