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Antigenic Specificity | ADAR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Double-stranded RNA-specific adenosine deaminase (ADAR) detection. Background: Double-stranded RNA-specific adenosine deaminase, also known as ADAR1, is an enzyme that in humans is encoded by the ADAR gene. It is mapped to 1q21.3. This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: E Coli-derived human ADAR1 recombinant protein (Position: S128-Q346). Human ADAR1 shares 90.2% and 50.7% amino acid (aa) sequence identity with mouse and rat ADAR1, respectively. |
Other Names | [Adar1; Adar 1; ADAR; AGS6; AV242451; DRADA; Dsh; Dsrad; G1P1; IFI4; IFI-4; IFI 4; P136; P55265; Double-stranded RNA-specific adenosine deaminase; adenosine deaminase, RNA-specific], [ADAR; ADAR; DSH; AGS6; G1P1; IFI4; P136; ADAR1; DRADA; DSRAD; IFI-4; K88DSRBP; ADAR1; DSRAD; G1P1; IFI4; DRADA; p136; IFI-4] |
Gene, Accession # | [ADAR], Gene ID: 103, NCBI: NP_001020278.1, UniProt: P55265 |
Catalog # | MBS178476 |
Price | $315 |
Order / More Info | ADAR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: ADAR Adenosine Deaminase Acting on RNA.2. Kim U, Wang Y, Sanford T, Zeng Y, Nishikura K (November 1994). Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. Proceedings of the National Academy of Sciences of the United States of America 91 (24): 11457-61. |