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Antigenic Specificity | Human Mixed lineage kinase domain-like |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity. |
Immunogen | Immunogen: Recombinant human Mixed lineage kinase domain-like protein(1-471AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-165025 |
Other Names | [hMLKL; MLKL], [MLKL; MLKL; hMLKL; hMLKL] |
Gene, Accession # | [MLKL], Gene ID: 197259, NCBI: NP_001135969.1, UniProt: Q8NB16 |
Catalog # | MBS1492460 |
Price | $160, $235 |
Order / More Info | Human Mixed lineage kinase domain-like Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |