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Antigenic Specificity | PAD4 (C-term), 512-544 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PAD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 512-544 amino acids from the C-terminal region of human PAD4. PAD4 is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalyzation of the deimination of the arginine residues. PAD4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response. |
Immunogen | n/a |
Other Names | [Protein-arginine deiminase type-4; HL-60 PAD; Peptidylarginine deiminase IV; Protein-arginine deiminase type IV; PADI4; PADI5; PDI5] |
Gene, Accession # | [PADI4], Gene ID: 23569, NCBI: NP_036519.2, UniProt: Q9UM07 |
Catalog # | MBS9201969 |
Price | $165, $370 |
Order / More Info | PAD4 (C-term), 512-544 Antibody from MYBIOSOURCE INC. |
Product Specific References | Nakayama-Hamada, M., et al., Biochem. Biophys. Res. Commun. 327(1):192-200 (2005). Wang, Y., et al., Science 306(5694):279-283 (2004). Arita, K., et al., Arthritis Rheum. 11(8):777-783 (2004). Barton, A., et al., Arthritis Rheum. 50(4):1117-1121 (2004). Suzuki, A., et al., Nat. Genet. 34(4):395-402 (2003). |