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Antigenic Specificity | NCBP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NCBP1 antibody is human, mouse and rat reactive. At least two isoforms of NCBP1 are known to exist; this antibody will detect both isoforms of NCBP1. NCBP1 Antibody: NCBP1, also known as CBP80, is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. NCBP1 promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay (1,2). Recent evidence has shown that cellular-cap-binding proteins such as NCBP1 associate with influenza virus mRNAs, suggesting that these viral mRNAs may follow the normal cellular pathways |
Immunogen | Immunogen: NCBP1 antibody was raised against a 17 amino acid peptide near the center of human NCBP1. Buffer: NCBP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [NCBP1; NCBP; Sto1; CBP80; NCBP; Nuclear cap-binding protein subunit 1; 80 kDa nuclear cap-binding protein; nuclear cap binding protein subunit 1, 80kDa], [NCBP1; NCBP1; NCBP; Sto1; CBP80; CBP80; NCBP; CBP80; NCBP 80 kDa subunit] |
Gene, Accession # | [NCBP1], Gene ID: 4686, NCBI: NP_002477, UniProt: Q09161 |
Catalog # | MBS153370 |
Price | $375 |
Order / More Info | NCBP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |