Edit |   |
---|---|
Antigenic Specificity | ZIP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ZIP3 Antibody: The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human |
Immunogen | Immunogen: ZIP3 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP3. Buffer: ZIP3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [ZIP3; ZIP3; ZIP-3; ZIP3; Zinc transporter ZIP3; Solute carrier family 39 member 3; solute carrier family 39 (zinc transporter), member 3], [SLC39A3; SLC39A3; ZIP3; ZIP-3; ZIP3; ZIP-3] |
Gene, Accession # | [SLC39A3], Gene ID: 29985, NCBI: NP_653165, UniProt: Q9BRY0 |
Catalog # | MBS151229 |
Price | $375 |
Order / More Info | ZIP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |