TRAF6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRAF6
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formation exchange purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionTRAF6 Antibody: Signals from the IL-1 receptor (IL-1R)/Toll-like receptor (TLR) and TNF receptor (TNFR) superfamilies are critical for regulating the function of antigen-presenting cells. Signals transduced by these molecules lead to increased expression and activation of transcription factors such as NF-κB. TNF receptor-associated factor 6 (TRAF6) is unique in that it is a signaling adapter molecule common to both families. TRAF6 is important in cytokine production, dendritic cell (DC) maturation, and the T cell stimulatory capacity of DCs in response to TLR and CD40 ligands. It can be activated in the IL-1R/TLR signaling pathway by IL-1 receptor-associated kinase 1 (IRAK-1) or by other TLR adaptor molecules such as TRIF. Also, it has
ImmunogenImmunogen: TRAF6 antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human TRAF6. Buffer: TRAF6 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[TRAF6; RNF85; MGC:3310; RNF85; E3 ubiquitin-protein ligase TRAF6; TNF receptor-associated factor 6], [TRAF6; TRAF6; RNF85; MGC:3310; RNF85]
Gene, Accession #[TRAF6], Gene ID: 7189, NCBI: NP_004611, UniProt: Q9Y4K3
Catalog #MBS150981
Price$375
Order / More InfoTRAF6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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