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Antigenic Specificity | TRAF6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRAF6 Antibody: Signals from the IL-1 receptor (IL-1R)/Toll-like receptor (TLR) and TNF receptor (TNFR) superfamilies are critical for regulating the function of antigen-presenting cells. Signals transduced by these molecules lead to increased expression and activation of transcription factors such as NF-κB. TNF receptor-associated factor 6 (TRAF6) is unique in that it is a signaling adapter molecule common to both families. TRAF6 is important in cytokine production, dendritic cell (DC) maturation, and the T cell stimulatory capacity of DCs in response to TLR and CD40 ligands. It can be activated in the IL-1R/TLR signaling pathway by IL-1 receptor-associated kinase 1 (IRAK-1) or by other TLR adaptor molecules such as TRIF. Also, it has |
Immunogen | Immunogen: TRAF6 antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human TRAF6. Buffer: TRAF6 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TRAF6; RNF85; MGC:3310; RNF85; E3 ubiquitin-protein ligase TRAF6; TNF receptor-associated factor 6], [TRAF6; TRAF6; RNF85; MGC:3310; RNF85] |
Gene, Accession # | [TRAF6], Gene ID: 7189, NCBI: NP_004611, UniProt: Q9Y4K3 |
Catalog # | MBS150981 |
Price | $375 |
Order / More Info | TRAF6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |