eIF2alpha (Phospho Ser51) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityeIF2alpha (Phospho Ser51)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
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DescriptionSpecificity: Phospho-eIF2alpha (S51) Polyclonal Antibody detects endogenous levels of eIF2alpha protein only when phosphorylated at S51. The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).
ImmunogenImmunogen: Synthesized peptide derived from human eIF2alpha around the phosphorylation site of S51
Other Names[Rabbit eIF2alpha (phospho Ser51); EIF2S1; EIF2A; Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; eIF-2A; eIF-2alpha]
Gene, Accession #[eIF2alpha], Gene ID: 1965, NCBI: NP_004085.1, UniProt: P05198
Catalog #MBS9700627
Price$250, $250
Order / More InfoeIF2alpha (Phospho Ser51) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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