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Antigenic Specificity | cFOS (2-17) |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | 1ug/ul |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antiserum shows a high level of specificity for cFOS confirmed by immunohostochemistry. FUNCTION: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. SUBUNIT: Heterodimer. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB. SUBCELLULAR LOCATION: Nucleus. INDUCTION: C-fos expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress an |
Immunogen | Immunogen: A synthetic peptide (MFSGFNADYEASSSRC; aa 2-17) conjugated to diphtheria toxoid has been used as the immunogen. The peptide is homologous with the corresponding sequence derived from cFos protein in rat, mouse, hamster and cat. Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide. |
Other Names | [cfos; Proto-oncogene c-Fos; proto-oncogene c-Fos; Fos proto-oncogene, AP-1 transcription factor subunit; Cellular oncogene fos; G0/G1 switch regulatory protein 7] |
Gene, Accession # | [cFOS], Gene ID: 2353, NCBI: AAC98315.1 |
Catalog # | MBS4152753 |
Price | $515 |
Order / More Info | cFOS (2-17) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |